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2-Bromo-α-ergocryptine methanesulfonate salt

B2134 -

solid

DOWNLOAD MSDS (PDF)

Synonym: (+)-2-Bromo-12′-hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)ergotaman-3′,6′-18-trione methanesulfonate salt, (+)-Bromocriptine methanesulfonate salt, Bromocriptine mesylate salt

  • CAS Number: 22260-51-1

  • Empirical Formula (Hill Notation): C32H40BrN5O5 · CH4SO3

  • Molecular Weight: 750.70

  • Beilstein Registry Number: 4115238

  • EC Number: 244-881-1

  • MDL number: MFCD00069218

  • PubChem Substance ID: 24277885

2-Bromo-α-ergocryptine methanesulfonate salt solid
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Properties

Related CategoriesAgonists, B, Bioactive Small Molecules, Cell Biology, Dopaminergics,
formsolid
optical activity[α]20/D +95°, c = 1 in methanol: methylene chloride (1:1)(lit.)
color white
solubilityH2O: soluble0.8 mg/mL
 ethanol: soluble23 mg/mL
storage temp.2-8°C
Gene InformationResearch your gene in Your Favorite Gene powered by Ingenuity
human ... DRD2(1813), DRD3(1814), PRL(5617)
Show all 8 properties

Description

Biochem/physiol Actions

Agonist at D2 and D3 dopamine receptors; inhibits prolactin secretion.

Price and Availability

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Documents

Certificate of Analysis

Certificate of Origin

Gene Information
Structure Search
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Safety Information

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements22-24/25
WGK Germany3
RTECSKE1595000
Technical information & documentation associated with this product is available in the Safety & Documentation tab.

References

Zhang, Y., Bromocriptine/SKF38393 treatment ameliorates dyslipidemia in ob/ob mice. Metabolism 48, 1033, (1999) Abstract

Perachon, S., et al., Functional potencies of new antiparkinsonian drugs at recombinant human dopamine D1, D2 and D3 receptors. Eur. J. Pharmacol. 366, 293, (1999) Abstract

Geurts, M., et al., Dopamine receptor-modulated [35S]GTPγS binding in striatum of 6-hydroxydopamine-lesioned rats. Brain Res. 841, 135-142, (1999) Abstract

Velasco, M. and Luchsinger, A., Dopamine: pharmacologic and therapeutic aspects. Am. J. Ther. 5, 37-43, (1996)

Merck 14,1416


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